AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg is approved by the U.S. Food and Drug Administration (FDA) as a treatment to help improve walking in patients with multiple sclerosis (MS). This was demonstrated by an increase in walking speed.
AMPYRA is the first and only prescription MS therapy that has been specifically approved by the FDA for this use. More than 400,000 people in the U.S. and nearly 2.5 million people worldwide are living with MS, and for the majority of those people, the disease affects their ability to walk. Walking difficulties can happen to anyone with MS, and can lead to difficulty in keeping up with family and friends, or having difficulty crossing the street. We are gratified to have been able to contribute to advancing the care of people with MS.
For more information, visit http://www.AMPYRA.com.
Do not take AMPYRA if you have ever had a seizure, have certain types of kidney problems, or are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.
Take AMPYRA exactly as prescribed by your doctor.
Before taking AMPYRA, tell your doctor if you
Stop taking AMPYRA and call your doctor right away if you have a seizure while taking AMPYRA. You could have a seizure even if you never had a seizure before. Your chance of having a seizure is higher if you take too much AMPYRA or if your kidneys have a mild decrease of function, which is common after age 50. Your doctor may do a blood test to check how well your kidneys are working before you start AMPYRA.
AMPYRA should not be taken with other forms of 4-aminopyridine (4-AP, fampridine), since the active ingredient is the same.
AMPYRA may cause serious side effects, including
The most common adverse events for AMPYRA in MS patients were urinary tract infection, trouble sleeping, dizziness, headache, nausea, weakness, back pain, problems with balance, multiple sclerosis relapse, burning, tingling, or itching of your skin, irritation in your nose and throat, constipation, indigestion, and pain in your throat.
Please see Patient Medication Guide for additional safety information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
AMPYRA is a registered trademark of Acorda Therapeutics, Inc.
AMPYRA is marketed by Acorda Therapeutics, Inc. and manufactured under license from Alkermes Pharma Limited (APIL), Ireland.